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THERMO POLARIS Q MANUAL


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Applications of Chromatography - Chrom Tech
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How Does Column Temperature Affect HPLC Resolution?
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Jan 27, 2022The balance of programmed death-1 (PD-1)-expressing CD8 + T cells and regulatory T (Treg) cells in the tumor microenvironment (TME) determines the clinical efficacy of PD-1 blockade therapy through the competition of their reactivation. However, factors that determine this balance remain unknown. Here, we show that Treg cells gain higher PD-1
Neoantigen-specific CD4+ T cells in human melanoma have
Apr 11, 2022Because isolation of tumor-specific T cells from tumor-infiltrating lymphocytes (TILs) or blood is challenging, we employed multiple approaches to identify and validate TCRVb sequences of neoantigen-specific CD4 + T cells (Figure S1A). PD-1 high CD4 + T cells, which have been shown to be enriched for tumor reactivity (Yossef et al., 2018), were sorted from

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